This is a big loss for the Arizona Cardinals.
According to Adam Schefter of ESPN, Cardinals WR DeAndre Hopkins is expected to miss the rest of the regular season with a sprained knee.
Schefter adds that Hopkins will seek a second opinion and hopes to be able to return for the postseason:
The 29-year-old has battled several injuries this season after being one of the most durable players at his position for years. If his regular season is over, he ends it with 42 catches for 572 yards receiving and eight touchdowns.